A vial of live lone star ticks being displayed. Photograph: Portland Press Herald/Getty Imagesby Oliver Milman
Blood-sucking ticks that trigger a bizarre
allergy to meat in the people they bite are exploding in number and
spreading across the US, to the extent that they could cover the entire
eastern half of the country and infect millions of people, experts have
warned.
Lone star ticks have taken advantage
of rising temperatures by the human-caused climate crisis to expand from
their heartland in the south-east US to areas previously too cold for
them, in recent years marching as far north as New York and even Maine, as well as pushing westwards.
The
ticks are known to be unusually aggressive and can provoke an allergy
in bitten people whereby they cannot eat red meat without enduring a
severe reaction, such as breaking out in hives and even the risk of heart attacks. The condition, known as alpha-gal syndrome, has proliferated from just a few dozen known cases in 2009 to as many as 450,000 now.
“We thought this thing was relatively rare 10
years ago but it’s become more and more common and it’s something I
expect to continue to grow very rapidly,” said Brandon Hollingsworth, an
expert at the University of South Carolina who has researched the tick’s expansion.
“We’ve
seen an explosive increase in these ticks, which is a concern. I
imagine alpha-gal will soon include the entire range of the tick, which
could become the entire eastern half of the US as there’s not much to
stop them. It seems like an oddity now but we could end up with millions
of people with an allergy to meat.”
The exact
number of alpha-gal cases is unclear due to patchy data collection but
it’s likely to be a severe undercount as people may not link their
allergic reaction to the tick bites. The Centers for Disease Control and
Prevention (CDC) has said around 110,000 cases have been documented since 2010 but acknowledges the true number could be as high as 450,000.
Cases
will rise further as the ticks spread, aided by their adaptability to
local conditions, according to Laura Harrington, an entomologist and
disease specialist at Cornell University. “With their adaptive nature
and increasing temperatures, I don’t see many limits to these ticks over
time,” she said.
A female lone star tick, or Amblyomma americanum collected in Maryland on 21 Jun 2017. Photograph: BSIP/Universal Images Group/Getty Images
Alpha-gal is a confounding condition because it
doesn’t cause an immediate allergic reaction, unlike a peanut allergy,
with symptoms often appearing several hours after consuming meat. The
syndrome is not caused by a pathogen but spurs an allergy to a sugar
molecule found in mammals and an array of other things, from toothpaste
to medical equipment. Researchers think the condition can wane over time
but is also worsened by further tick bites.
This
leads to a confusing and fraught experience for the growing number of
Americans with alpha-gal, who are now girding for another expected hot
summer full of ticks. “The ticks are rampant this year, I’ve pulled 10
ticks off me this season alone, it feels like they are uncontrollable at
the moment,” said Heather O’Bryan, a horticulturist in Roanoke,
Virginia, who has alpha-gal. “They are so disgusting. I’m not afraid of a
lot, but I’m afraid of ticks.”
In 2019,
O’Bryan suffered full body hives and struggled to breathe after eating a
pork sausage. “It was terrifying experience, I didn’t know I had an
allergy but it almost killed me,” she said. She now avoids products
containing mammal-derived elements, such as certain toothpastes and even
toilet paper, due to adverse reactions.
Dairy,
another mammalian product, is also off limits. “I’ve learned what I can
eat now, but I was so sad when I realized I couldn’t have pizza again, I
remember crying in front of a frozen pizza in the supermarket aisle,”
she said.
There is now an “almost constant”
stream of new members to the Facebook alpha-gal support groups that
O’Bryan is part of, she said, with her region of Virginia now seemingly
saturated by the condition. “Everyone knows someone who has it, I talk a
friend off a ledge once a month when they’ve been bitten because they
are so afraid they have it and are freaking out,” she said.
Lone
star ticks are aggressive and can speedily follow a human target if
they detect them. “They will hunt you, they are like a cross between a
lentil and a velociraptor,” said Sharon Pitcairn Forsyth, a
conservationist who lives in the Washington DC area.
A
particular horror is the prospect of brushing up against vegetation
containing a massed ball of juvenile lone star ticks, know as a “tick
bomb”, that can deliver thousands of tick bites. “They are so tiny you
can’t see them but you have to take it seriously or you’ll never get
them off you,” said Forsyth, who now carries around a lint roller to
remove such clusters.
After being diagnosed with alpha-gal, Forsyth set up online resources about the condition to help spread awareness and advocate
for better food labeling to include alpha-gal warnings. “I get calls
from doctors asking questions about this because they just don’t know about it,” she said. “I’m not a medical professional, so I just send them the research papers.”
As
the climate heats up, due to the burning of fossil fuels, ticks are
able to shift to areas that are becoming agreeably warm for them.
Growing numbers of deer, which host certain ticks, and sprawling housing
development into natural habitats is also causing more interactions
with ticks. “Places where houses push up against habitats and parks
where nature has regrown are where we are seeing cases,” said
Hollingsworth.
But
much is still unknown, such as why lone star ticks, which have long
been native to the US, suddenly started causing these allergic
reactions. Symptoms can also be alarmingly varied – Forsyth said she
rarely eats out now because of concerns of contamination in the food and
even that alpha-gal could be carried to her airborne, via the steam of
cooked meat.
“Some people are scared to leave
the house, it’s hard to avoid,” she said. “Many people who get it are
over 50, so the first symptom some of them have is a heart attack.”
So how far can alpha-gal spread? Cases have been found in Europe and Australia,
although in low numbers, while in the US it’s assumed lone star ticks
won’t be able to shift west of the Rocky mountains. But other tick
species might also be able to spread alpha-gal syndrome – a recent scientific paper found the western black legged tick and the black legged tick, also called the deer tick, could also cause the condition.
Hanna Oltean, an epidemiologist at Washington state department of health, said
it was “very surprising” to find a case of alpha-gal in Washington
state from a person bitten by a tick locally, suggesting the western
black legged tick could be a culprit.
“The
range is spreading and emerging in new areas so the risk is increasing
over time,” Oltean said. “Washington state is very far from the range
and the risk remains very low here. But we don’t know enough about the
biology of how ticks spread the syndrome.”
The
spread of alpha-gal comes amid a barrage of disease threats from
different ticks that are fanning out across a rapidly warming US.
Powassan virus, which can kill people via an inflammation of the brain,
is still rare but is growing, as is Babesia, a parasite that causes
severe illnesses. Lyme disease, long a feature of the US north-east, is
also burgeoning.
“We are dealing with a lot of serious tick-borne illnesses and discovering new ones all the time,” said Harrington.
“There’s
a tremendous urgency to confront this with new therapies but the
problem is we are going backwards in terms of funding and support in the
US. There have been cuts to the CDC and NIH (National Institutes of Health) which means there is decreasing support. It’s a major concern.”